Abstract Engineered microenvironments: From 3D culture models to biomanufacturing The microenvironments that cells experience in the human body, which vary in structure, stiffness, and biochemical content, are instrumental in cell function and fate in disease processes, from scar tissue formation in the lungs that leads to fibrosis to the re-activation of dormant disseminated tumor cells…

Abstract Sustainability and Energy Transition in the Chemical Industry Today’s market and stakeholder demands require institutions to produce materials more sustainably, with demonstrated progress towards reductions in greenhouse gas emissions, lower water use, and improved ability to recycle products at the end-of-life.  Dow has embarked on a “decarbonize and grow” strategy that will drive towards…

Abstract John’s seminar will share key insights from his career in manufacturing including the impact of his NC State engineering experience, learnings from a career of acquiring key skills, and how he views the future of manufacturing in which our Engineering department can better prepare and position NC State graduates for success. Biography John Wolf…

Abstract Engineering Immune System Development Engineered T cells are at the leading edge of clinical cell therapy. T cell therapies have had a remarkable impact on patient care for a subset of hematological malignancies. This foundation has motivated the development of off-the-shelf engineered cell therapies for a broad range of devastating indications. Achieving this vision…

Abstract Solute Diffusion in Block Copolymer Organogels Through the Lens of Transdermal Drug Delivery Effective transdermal drug delivery patches must exhibit multiple characteristics including the ability to store and release desired pharmaceutical compounds, enhance permeation of those compounds through skin, and moderately adhere to skin while avoiding irritation. Gels composed of styrenic block copolymers and…