{"id":53,"date":"2016-12-12T12:06:17","date_gmt":"2016-12-12T17:06:17","guid":{"rendered":"https:\/\/cbe.ncsu.edu\/velevgroup\/?page_id=53"},"modified":"2021-05-19T01:00:15","modified_gmt":"2021-05-19T05:00:15","slug":"microfluidics-bioassays","status":"publish","type":"page","link":"https:\/\/cbe.ncsu.edu\/velevgroup\/research\/microfluidics-bioassays\/","title":{"rendered":"Microfluidics & Bioassays"},"content":{"rendered":"\n

Research Description<\/span><\/h2>\n\n\n\n

The Velev group is among the first to explore and demonstrate the formation of electrically-functional microdevices by interfacing colloidal assemblies with on-chip electronic circuits.  <\/sup>Microscopic electronically readable biosensors have been assembled in situ<\/em> by dielectrophoresis. <\/p>\n\n\n\n

Current Projects<\/span><\/h2>\n\n\n\n

Paper Microfluidic Based Wearable Patches for Biomarker Detection from Sweat <\/strong> Sneha Mukherjee<\/a><\/p>\n\n\n\n

Microfluidic Sweat Monitoring<\/strong> Tamoghna Saha<\/a><\/p>\n\n\n\n

Previous Projects<\/span><\/h2>\n\n\n\n

Novel Human-Device Interfaces: Hydrogel EKG Electrodes and Microfluidic Sweat Monitoring<\/strong> Timothy Shay<\/a><\/p>\n\n\n\n

Cell Sensing and Manipulation Using AC Electric Fields<\/strong> Elizabeth Melvin<\/a><\/p>\n\n\n\n

Thin Film Nanofluidics<\/strong> Jairus Kleinert<\/a><\/p>\n\n\n\n

Silver-Enhanced Immunoassays for Analyte Detection<\/strong> Shalini Gupta<\/a><\/p>\n\n\n\n

Quantitative Micro-bioassays Needing Only Microliter Volumes of Analyte for Biomoleculer Detection<\/strong> Vinayak Rastogi<\/a><\/p>\n\n\n\n

Manipulation of Droplets with Suspended Particles on a Dielectrophoretic Liquid Chip<\/strong> Suk Tai Chang<\/a><\/p>\n\n\n\n

AC Electrokinetic Technique for Particle Collection on Patterned Electrodes<\/strong> Ketan Bhatt<\/a><\/p>\n\n\n\n

Representative Publications<\/span><\/h2>\n\n\n\n

Sharma, R.; Blackburn, T.; Hu, W.; Wiltberger, K.; Velev, O.D. On-chip microelectrode impedance analysis of mammalian cell viability during biomanufacturing. Biomicrofluidics.<\/em> 2014<\/strong>, 8<\/em>, 054108.<\/a> <\/p>\n\n\n\n

Gupta, S.; Kilpatrick,P. K.; Melvin, E. M.; Velev, O. D. On-chip latex agglutination immunoassay readout by electrochemical impedance spectroscopy. Lab on a Chip<\/em> 2012<\/strong>, 12<\/em>, 4279-4286.<\/a> <\/p>\n\n\n\n

Gupta, S.; Alargova, R. G.; Kilpatrick, P. K.; Velev, O. D. On-chip dielectrophoretic coassembly of live cells and particles into responsive biomaterials. Langmuir<\/em> 2010<\/strong>, 26<\/em>, 3441\u20133452.<\/a> <\/p>\n\n\n\n

Gupta, S.; Alargova, R. G.; Kilpatrick, P. K.; Velev, O. D. On-chip electric field driven assembly of biocomposites from live cells and functionalized particles. Soft Matter<\/em> 2008<\/strong>, 4<\/em>, 726\u2013730.<\/a> <\/p>\n\n\n\n

Gupta, S.; Huda, S.; Kilpatrick, P. K.; Velev, O. D. Characterization and optimization of gold nanoparticle-based silver-enhanced immunoassays. Analytical Chemistry<\/em> 2007<\/strong>, 79<\/em>, 3810\u20133820.<\/a> <\/p>\n","protected":false},"excerpt":{"rendered":"

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